Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8636522 | 0.99 | MAOB (0.48) | MAOBMAOASCN9ABCHESLC2A1 | |
| SCHEMBL8640665 | 0.95 | MAOB (0.49) | MAOBMAOASCN9ABCHE | |
| SCHEMBL1672184 | 0.89 | MAOB (0.62) | MAOBMAOASCN9ABCHE | |
| SCHEMBL2940856 | 0.89 | MAOB (0.62) | MAOBMAOASCN9ABCHE | |
| SCHEMBL1665718 | 0.89 | MAOB (0.62) | MAOBMAOASCN9ABCHE | |
| SCHEMBL8636498 | 0.88 | FAAH (0.42) | BCHE | |
| SCHEMBL8637818 | 0.88 | SLC2A1 (0.47) | SLC2A1 | |
| SCHEMBL9133931 | 0.88 | SLC2A1 (0.53) | BCHESLC2A1 | |
| SCHEMBL8638563 | 0.88 | MEN1 (0.49) | BCHESLC2A1 | |
| Water SCHEMBL1672445 | 0.88 | MAOB (0.61) | MAOBMAOASCN9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| EP-0643688-A1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-03-22 | — | — | EP | disclosed |
| WO-1994022808-A1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | FARMITALIA CARLO ERBA SRL (IT) | 1994-10-13 | — | — | WO | disclosed |