Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.60 |
| ▸ | SKP1 | P63208 | 2/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16651683 | 0.82 | ACHE (0.60) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL16651989 | 0.80 | PTPN11 (0.53) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL3274585 | 0.80 | ACHE (0.66) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL20818663 | 0.77 | CKS1B (0.58) | CKS1BSKP1SKP2ACHEGPR119 | |
| SCHEMBL16651654 | 0.77 | PTPN11 (0.57) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL1447940 | 0.77 | GPR119 (0.65) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL21551531 | 0.76 | PTPN11 (0.53) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL29890873 | 0.76 | PTPN11 (0.53) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL16654621 | 0.76 | GPR119 (0.58) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL16653817 | 0.76 | GPR119 (0.61) | CKS1BSKP1SKP2PTPN11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058129-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | BLUEPRINT MEDICINES CORPORATION (US) | 2015-04-23 | — | — | WO | disclosed |