Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 10/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743783 | 0.82 | JAK3 (0.42) | CA1CA2CA7JAK3BTK | |
| SCHEMBL6631742 | 0.81 | JAK3 (0.52) | CA1CA2CA7JAK3BTK | |
| SCHEMBL836447 | 0.81 | JAK3 (0.52) | CA1CA2CA7JAK3BTK | |
| SCHEMBL836446 | 0.81 | JAK3 (0.52) | CA1CA2CA7JAK3BTK | |
| SCHEMBL20028616 | 0.80 | CTSS (0.54) | CA1CA2CA7JAK3BTK | |
| SCHEMBL12189209 | 0.80 | CTSS (0.54) | CA1CA2CA7JAK3BTK | |
| SCHEMBL1204596 | 0.80 | CTSS (0.54) | CA1CA2CA7JAK3BTK | |
| SCHEMBL1204594 | 0.80 | CTSS (0.54) | CA1CA2CA7JAK3BTK | |
| SCHEMBL19859640 | 0.79 | CA1 (0.56) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL153320 | 0.79 | JAK3 (0.44) | CA1CA2CA7JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057585-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-04-23 | — | — | WO | disclosed |