SCHEMBL16655018

SCHEMBL16655018

Nc1ccn([C@]2(CO)O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.43
POLB P06746 1/20 0.43
P2RY2 P41231 5/20 0.41
ADSS2 P30520 1/20 0.40
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
MTOR P42345 1/20 0.39
MDM2 Q00987 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
TSHR P16473 1/20 0.39
GLA P06280 1/20 0.39
P2RY6 Q15077 3/20 0.38
P2RY4 P51582 2/20 0.38
PDE4D Q08499 1/20 0.38
PDE3A Q14432 1/20 0.38
SLC29A1 Q99808 1/20 0.38
ST6GAL1 P15907 1/20 0.37
POLG P54098 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL21248625 0.88 LMNA (0.44) POLA1POLBP2RY2LMNATHRB
Phosphoric Acid SCHEMBL16655013 0.87 LMNA (0.47) POLA1POLBP2RY2LMNATHRB
Phosphoric Acid SCHEMBL21645281 0.87 LMNA (0.47) POLA1POLBP2RY2LMNATHRB
SCHEMBL3272285 0.84 LMNA (0.51) POLA1POLBLMNATHRBMTOR
SCHEMBL9515900 0.84 POLB (0.43) POLA1POLBP2RY2ADSS2TSHR
SCHEMBL13234931 0.84 POLA1 (0.44) POLA1POLBP2RY2ADSS2LMNA
SCHEMBL12354843 0.84 POLA1 (0.44) POLA1POLBP2RY2ADSS2LMNA
SCHEMBL30194983 0.84 POLA1 (0.46) POLA1POLBP2RY2ADSS2LMNA
SCHEMBL12363580 0.84 POLA1 (0.44) POLA1POLBP2RY2ADSS2LMNA
SCHEMBL17027893 0.84 POLA1 (0.44) POLA1POLBP2RY2ADSS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118891-A1 METHOD OF CHARACTERISING POLYPEPTIDES USING A NANOPORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-06-29 WO disclosed
CN-107699532-A 3,7 dihydroxy Zhuo phenolic ketone superior strains and its fermentation culture method 上海交通大学 2018-02-16 CN disclosed
CN-107699581-A 3,7 dihydroxy Zhuo phenolic ketone biological synthesis gene clusters and its application 上海交通大学 2018-02-16 CN disclosed
EP-3058090-A1 METHOD OF CHARACTERIZING A TARGET RIBONUCLEIC ACID (RNA) COMPRISING FORMING A COMPLEMENTARY POLYNUCLEOTIDE WHICH MOVES THROUGH A TRANSMEMBRANE PORE Oxford Nanopore Technologies Limited (GB) 2016-08-24 EP disclosed
WO-2015056028-A1 METHOD OF CHARACTERIZING A TARGET RIBONUCLEIC ACID (RNA) COMPRISING FORMING A COMPLEMENTARY POLYNUCLEOTIDE WHICH MOVES THROUGH A TRANSMEMBRANE PORE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-04-23 WO disclosed