SCHEMBL17027893

SCHEMBL17027893

C[C@@]1(n2ccc(N)nc2=O)O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.44
POLB P06746 1/20 0.43
P2RY2 P41231 7/20 0.43
P2RY6 Q15077 4/20 0.43
P2RY4 P51582 3/20 0.41
TSHR P16473 1/20 0.41
GLA P06280 1/20 0.41
ADSS2 P30520 1/20 0.41
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
MTOR P42345 1/20 0.38
MDM2 Q00987 1/20 0.38
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13234931 1.00 POLA1 (0.44) POLA1POLBP2RY2P2RY6P2RY4
SCHEMBL12354843 1.00 POLA1 (0.44) POLA1POLBP2RY2P2RY6P2RY4
SCHEMBL12363580 1.00 POLA1 (0.44) POLA1POLBP2RY2P2RY6P2RY4
SCHEMBL18394211 0.90 P2RY2 (0.51) POLBP2RY2P2RY6P2RY4
SCHEMBL13815856 0.87 POLA1 (0.38) POLA1POLBP2RY2P2RY6P2RY4
SCHEMBL4248196 0.87 FGFR1 (0.39) POLA1POLBP2RY2P2RY6P2RY4
SCHEMBL13805632 0.87 POLA1 (0.38) POLA1POLBP2RY2P2RY6P2RY4
Phosphoric Acid SCHEMBL17027889 0.86 LMNA (0.47) POLA1POLBP2RY2TSHRLMNA
Phosphoric Acid SCHEMBL18438955 0.86 LMNA (0.47) POLA1POLBP2RY2TSHRLMNA
SCHEMBL9515900 0.85 POLB (0.43) POLA1POLBP2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
CN-106232834-B Sample preparation method 牛津纳米孔技术公司 2020-09-22 CN claimed
EP-3108010-B1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECH LTD (GB) 2018-11-28 EP claimed
EP-3108010-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2016-12-28 EP claimed
CN-106232834-A Sample preparation methods 牛津纳米孔技术公司 2016-12-14 CN claimed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN disclosed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US disclosed
US-11542551-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-01-03 US disclosed
US-20200318179-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-10-08 US disclosed
CN-106232834-B Sample preparation method 牛津纳米孔技术公司 2020-09-22 CN disclosed
US-10669578-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-06-02 US disclosed
EP-3108010-B1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECH LTD (GB) 2018-11-28 EP disclosed
US-20170067101-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2017-03-09 US disclosed
EP-3108010-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2016-12-28 EP disclosed
CN-106232834-A Sample preparation methods 牛津纳米孔技术公司 2016-12-14 CN disclosed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM POLA1 19/4885POLB 4/4885P2RY2 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.