Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093359 | 0.84 | RORC (0.55) | RORCMCHR1 | |
| SCHEMBL16632703 | 0.82 | RORC (0.53) | RORC | |
| SCHEMBL16632874 | 0.80 | RORC (0.55) | RORC | |
| SCHEMBL15648267 | 0.75 | CYP1A2 (0.52) | RORC | |
| SCHEMBL21574646 | 0.74 | RORC (0.51) | RORC | |
| SCHEMBL28093128 | 0.73 | RORC (0.47) | RORC | |
| SCHEMBL21574758 | 0.72 | RORC (0.44) | RORC | |
| SCHEMBL21574595 | 0.71 | RORC (0.40) | RORC | |
| SCHEMBL16640876 | 0.70 | RORC (0.60) | RORC | |
| SCHEMBL16460927 | 0.70 | RORC (0.69) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica N.V. (BE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057205-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |