Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632703 | 0.78 | RORC (0.53) | RORCALDH1A1L3MBTL1DHFR | |
| SCHEMBL28093359 | 0.76 | RORC (0.55) | RORCALDH1A1L3MBTL1DHFR | |
| SCHEMBL21574646 | 0.74 | RORC (0.51) | RORCALDH1A1L3MBTL1 | |
| SCHEMBL21075983 | 0.72 | RORC (0.55) | RORC | |
| SCHEMBL21574758 | 0.72 | RORC (0.44) | RORC | |
| SCHEMBL16655198 | 0.71 | RORC (0.51) | RORC | |
| SCHEMBL15648267 | 0.70 | CYP1A2 (0.52) | RORC | |
| SCHEMBL21004772 | 0.70 | ALDH1A1 (0.49) | RORCALDH1A1L3MBTL1 | |
| SCHEMBL16632874 | 0.68 | RORC (0.55) | RORC | |
| SCHEMBL28093128 | 0.67 | RORC (0.47) | RORCL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-B1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-20 | — | — | EP | disclosed |