Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.51 |
| ▸ | ATR | Q13535 | 5/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655262 | 1.00 | BTK (0.51) | BTKPIK3CDATRRET | |
| SCHEMBL16655768 | 0.91 | BTK (0.51) | BTKPIK3CDATRRET | |
| SCHEMBL16655770 | 0.91 | BTK (0.51) | BTKPIK3CDATRRET | |
| SCHEMBL16655808 | 0.85 | BTK (0.50) | BTKPIK3CDATRRET | |
| SCHEMBL16655809 | 0.85 | BTK (0.50) | BTKPIK3CDATRRET | |
| SCHEMBL23908629 | 0.84 | BTK (0.53) | BTKPIK3CDATR | |
| SCHEMBL16655395 | 0.84 | PIK3CD (0.54) | BTKPIK3CDATRRET | |
| SCHEMBL16655394 | 0.84 | PIK3CD (0.54) | BTKPIK3CDATRRET | |
| SCHEMBL16655966 | 0.75 | BTK (0.66) | BTKPIK3CDATR | |
| SCHEMBL16654522 | 0.75 | JAK2 (0.62) | BTKPIK3CDATRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |