Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.50 |
| ▸ | ATR | Q13535 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655809 | 1.00 | BTK (0.50) | BTKPIK3CDATREGFRRET | |
| SCHEMBL16655768 | 0.85 | BTK (0.51) | BTKPIK3CDATREGFRRET | |
| SCHEMBL16655770 | 0.85 | BTK (0.51) | BTKPIK3CDATREGFRRET | |
| SCHEMBL16655263 | 0.85 | BTK (0.51) | BTKPIK3CDATRRET | |
| SCHEMBL16655262 | 0.85 | BTK (0.51) | BTKPIK3CDATRRET | |
| SCHEMBL23908629 | 0.81 | BTK (0.53) | BTKPIK3CDATR | |
| SCHEMBL16655395 | 0.81 | PIK3CD (0.54) | BTKPIK3CDATRRET | |
| SCHEMBL16655394 | 0.81 | PIK3CD (0.54) | BTKPIK3CDATRRET | |
| SCHEMBL16655779 | 0.69 | BTK (0.53) | BTKPIK3CDATREGFRSRC | |
| SCHEMBL16655577 | 0.69 | BTK (0.67) | BTKPIK3CDATREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |