Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 5/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565697 | 0.85 | KDM5B (0.37) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL21565690 | 0.82 | QPCT (0.36) | QPCTQPCTLBRD4CREBBPPDK1 | |
| SCHEMBL23123086 | 0.78 | QPCT (0.51) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL21387732 | 0.78 | BRD4 (0.40) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL21373612 | 0.75 | BRD4 (0.35) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL22901539 | 0.75 | KDM4E (0.40) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL6008269 | 0.75 | MAPT (0.50) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL31143361 | 0.75 | MAPT (0.50) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL2810219 | 0.74 | QPCT (0.41) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL16806030 | 0.74 | MAPT (0.41) | PDK1PDK2PDK3PDK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3568133-B1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH ZUERICH (CH) | 2023-12-13 | — | — | EP | disclosed |
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | disclosed |