Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30691886 | 0.87 | MAPT (0.32) | CXCR2MAPTSMN1; SMN2KDM4EGALR3 | |
| SCHEMBL170975 | 0.85 | MAPT (0.38) | CXCR2MAPTSMN1; SMN2KDM4EGALR3 | |
| SCHEMBL173254 | 0.84 | HSD11B1 (0.39) | CXCR2HSD11B1SLC34A1 | |
| SCHEMBL29368758 | 0.84 | HSD11B1 (0.39) | CXCR2HSD11B1SLC34A1 | |
| SCHEMBL29097531 | 0.84 | HSD11B1 (0.42) | CXCR2HSD11B1 | |
| SCHEMBL170971 | 0.83 | SLC34A1 (0.37) | MAPTSMN1; SMN2KDM4EGALR3HTT | |
| SCHEMBL29367616 | 0.83 | MAPT (0.35) | BRD4CXCR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14956153 | 0.83 | MAPT (0.35) | BRD4CXCR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL20471594 | 0.81 | MEN1 (0.36) | MAPTSMN1; SMN2KDM4EGALR3HTT | |
| SCHEMBL173247 | 0.81 | CRHR1 (0.40) | CXCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057424-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055707-A9 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | BAYER CROPSCIENCE AG (DE) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015055707-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |