Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.73 |
| ▸ | CCR5 | P51681 | 1/20 | 0.73 |
| ▸ | CCR8 | P51685 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40864 | 0.85 | KDM4E (0.46) | CCR1CCR5CCR8HDAC6METAP2 | |
| Abametapir SCHEMBL351152 | 0.85 | CCR1 (1.00) | CCR1CCR5CCR8HDAC6METAP2 | |
| Abametapir SCHEMBL29374261 | 0.85 | CCR1 (1.00) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL2482741 | 0.83 | CCR1 (0.60) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL1772787 | 0.83 | SMN1; SMN2 (0.49) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL14804379 | 0.80 | CCR1 (0.89) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL1456103 | 0.78 | CCR1 (0.84) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL15583204 | 0.77 | CCR1 (0.42) | CCR1CCR5CCR8HDAC6ALDH1A1 | |
| SCHEMBL29442916 | 0.76 | KDM4E (0.40) | CCR1CCR5CCR8HDAC6ALDH1A1 | |
| SCHEMBL4384001 | 0.75 | CCR1 (0.40) | CCR1CCR5CCR8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9406943-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150194681-A1 | ELECTROCATALYSTS USING POROUS POLYMERS AND METHOD OF PREPARATION | UCHICAGO ARGONNE, LLC (US) | 2015-07-09 | — | — | US | disclosed |
| US-9012344-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2015-04-21 | — | — | US | disclosed |