Abametapir

Abametapir

SCHEMBL29374261

Cc1ccc(-c2ccc(C)cn2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 1.00
CCR5 P51681 3/20 1.00
CCR8 P51685 3/20 1.00
HDAC6 Q9UBN7 1/20 1.00
METAP2 P50579 1/20 0.64
CYP3A4 P08684 1/20 0.56
CYP2A6 P11509 1/20 0.56
NOS3 P29474 1/20 0.55
NOS2 P35228 1/20 0.55
GRM5 P41594 2/20 0.44
ADRA2A P08913 2/20 0.43
ADRA2B P18089 2/20 0.43
ADRA2C P18825 2/20 0.43
PLAU P00749 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
ACHE P22303 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGS2 P35354 2/20 0.40
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Abametapir SCHEMBL351152 1.00 CCR1 (1.00) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL14804379 0.94 CCR1 (0.89) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL1456103 0.92 CCR1 (0.84) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL14804380 0.87 CCR1 (0.76) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17051514 0.86 CCR1 (0.75) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17051502 0.85 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL14804374 0.85 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL28454095 0.85 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL8025640 0.85 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL16656145 0.85 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP claimed
CN-119061388-B High-stability electroless copper plating solution and preparation method thereof 惠州金晟新电子科技有限公司 2025-03-28 CN claimed
WO-2024256358-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. HOFFMANN-LA ROCHE AG (CH) 2024-12-19 WO claimed
CN-119061388-A High-stability electroless copper plating solution and preparation method thereof 惠州金晟新电子科技有限公司 2024-12-03 CN claimed
CN-118930466-A Alkynyl thiosulfonate with photosensitivity and thermal stability and preparation method thereof 太原理工大学 2024-11-12 CN claimed
CN-118599108-A Cationic polymer with ultrahigh adsorption capacity and preparation and application thereof 中国矿业大学 2024-09-06 CN claimed
EP-4380916-A1 METHOD FOR PRODUCING FATTY ALDEHYDES AND DERIVATIVES THEREOF FMC Agricultural Solutions A/S (DK) 2024-06-12 EP claimed
CN-118047825-A Preparation method of desacetyl erigeron glycoside 威智医药股份有限公司 2024-05-17 CN claimed
CN-116676795-B Dyeing process of polyester-cotton blended fabric 宜兴市新伟隆印染有限公司 2024-04-26 CN claimed
CN-114569612-B Application of bipyridine in preventing and treating silkworm maggot disease 江苏科技大学 2024-02-27 CN claimed
CN-115477600-B Preparation method of benzyl thioether compound 浙江理工大学 2023-12-19 CN claimed
CN-116676795-A Dyeing process of polyester-cotton blended fabric 宜兴市新伟隆印染有限公司 2023-09-01 CN claimed
CN-113999276-B Purification method and preparation method of desacetyl erigeron glycoside intermediate 威智医药股份有限公司 2023-08-15 CN claimed
WO-2023012151-A1 METHOD FOR PRODUCING FATTY ALDEHYDES AND DERIVATIVES THEREOF BIOPHERO APS (DK) 2023-02-09 WO claimed
CN-115477600-A Preparation method of benzyl sulfide compound 浙江理工大学 2022-12-16 CN claimed
CN-115353598-A Bimetallic coordination porphyrin-based D-A conjugated polymer and preparation method and application thereof 苏州大学 2022-11-18 CN claimed
CN-113321788-B Four D-A' -pi-A type polymerization bipyridine metal complex dye sensitizers and preparation method and application thereof 湘潭大学 2022-05-10 CN claimed
CN-110256489-B Preparation method of alkyl phosphonyl 苏州大学 2022-03-08 CN claimed
CN-111962051-B Chemical copper plating solution for heterojunction solar battery and preparation method thereof 广州三孚新材料科技股份有限公司 2022-02-08 CN claimed
CN-113999276-A Purification method and preparation method of deacetyl hairy flower glycoside intermediate 威智医药有限公司 2022-02-01 CN claimed