Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.62 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237283 | 1.00 | DYRK1A (0.62) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL29577825 | 1.00 | DYRK1A (0.62) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL13642233 | 0.89 | DYRK1A (0.61) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL16656153 | 0.87 | MAOB (0.54) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL7005392 | 0.86 | ALDH1A1 (0.60) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL25843203 | 0.77 | MAOB (0.68) | MAPTALDH1A1KMT2ATDP1LMNA | |
| SCHEMBL11501581 | 0.77 | MAPT (0.75) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL9566898 | 0.77 | DYRK1A (1.00) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL11501580 | 0.77 | MAPT (0.75) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 | |
| SCHEMBL9786539 | 0.76 | DYRK1A (0.62) | DYRK1ADYRK2DYRK1BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9011925-B2 | Method for preparing polysaccharide nanocomposite particles and uses of the same | CHINA MEDICAL UNIVERSITY (TW) | 2015-04-21 | — | — | US | disclosed |