Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12108751 | 0.84 | KMT2A (0.66) | KMT2ANPC1RAB9AHPGDSTP53 | |
| SCHEMBL16601621 | 0.83 | KMT2A (0.44) | KMT2ALRRK2PTGS1PTGS2FYN | |
| SCHEMBL13151876 | 0.80 | KMT2A (0.71) | KMT2ANPC1RAB9AHPGDSTP53 | |
| SCHEMBL16601684 | 0.77 | USP7 (0.56) | KMT2AMAP4K4NPC1RAB9AHPGDS | |
| SCHEMBL16601622 | 0.77 | KMT2A (0.48) | KMT2AMAP4K4NPC1RAB9APTGS1 | |
| SCHEMBL12556925 | 0.77 | NPC1 (0.50) | KMT2AMAP4K4LRRK2NPC1RAB9A | |
| SCHEMBL6598757 | 0.76 | KMT2A (0.66) | KMT2ANPC1RAB9AHPGDSTP53 | |
| SCHEMBL16601623 | 0.75 | TDP2 (0.66) | KMT2APTGS1PTGS2CCR1CCR5 | |
| SCHEMBL23197472 | 0.74 | RPS6KA3 (0.42) | MAP4K4LRRK2NPC1RAB9APDGFRB | |
| SCHEMBL15764218 | 0.73 | FYN (0.47) | MAP4K4FYNGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |