Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1R1 | P14778 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656237 | 0.83 | DPP4 (0.42) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL16656578 | 0.82 | MGAM (0.41) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL16656236 | 0.82 | APP (0.39) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15082778 | 0.82 | APP (0.39) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL16656234 | 0.81 | IL1R1 (0.42) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15082779 | 0.79 | IL1R1 (0.48) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15085212 | 0.77 | RXFP1 (0.34) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15082787 | 0.73 | RXFP1 (0.34) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15082768 | 0.73 | MAPT (0.33) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL18803005 | 0.70 | IL1R1 (0.54) | IL1R1KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012773-B2 | Thiazole-based compound and uses thereof | NEC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |