Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656234 | 0.92 | IL1R1 (0.42) | IL1R1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16656574 | 0.83 | MAPT (0.44) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL16656236 | 0.83 | APP (0.39) | DPP4IL1R1ALDH1A1MAPTKMT2A | |
| SCHEMBL15082778 | 0.83 | APP (0.39) | DPP4IL1R1ALDH1A1MAPTKMT2A | |
| SCHEMBL16656233 | 0.83 | IL1R1 (0.40) | IL1R1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15085214 | 0.80 | ALDH1A1 (0.49) | IL1R1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15082789 | 0.77 | ALDH1A1 (0.55) | IL1R1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16656575 | 0.74 | MAPT (0.47) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL15082768 | 0.74 | MAPT (0.33) | IL1R1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15082779 | 0.72 | IL1R1 (0.48) | IL1R1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012773-B2 | Thiazole-based compound and uses thereof | NEC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |