Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667415 | 0.84 | NR3C1 (0.46) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL1667447 | 0.81 | HPGD (0.51) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL5140180 | 0.79 | NR3C1 (0.46) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL5056015 | 0.76 | CNR2 (0.45) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL14441143 | 0.76 | MEN1 (0.52) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL14441142 | 0.75 | HSP90AB1 (0.54) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL5133769 | 0.75 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL6948922 | 0.74 | CNR2 (0.46) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL3821565 | 0.74 | YTHDC1 (0.57) | MEN1KMT2AL3MBTL1ADORA2AHPGD | |
| SCHEMBL30834262 | 0.73 | ADORA2A (0.49) | MEN1KMT2AL3MBTL1ADORA2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891042-B1 | 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR THERAPEUTIC USE ON THE CENTRAL NERVOUS SYSTEM | UCB PHARMA SA (BE) | 2013-10-02 | — | — | EP | disclosed |
| EP-2308870-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308867-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |