Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463143 | 1.00 | HTT (0.57) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL16656814 | 1.00 | HTT (0.57) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL30674371 | 0.85 | HTT (0.61) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL13209087 | 0.85 | HTT (0.61) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL16656376 | 0.85 | HTT (0.61) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL16656359 | 0.85 | HTT (0.61) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| Oxalic Acid SCHEMBL10445493 | 0.80 | HTT (0.55) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL12124883 | 0.78 | HTT (0.55) | HTTALDH1A1XBP1RAB9ATSHR | |
| SCHEMBL6475089 | 0.77 | HTT (0.49) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL11007928 | 0.76 | ALDH1A1 (0.48) | HTTALDH1A1XBP1RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | NATIONAL SCIENCE FOUNDATION | 2021-01-14 | — | — | US | disclosed |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-10-17 | — | — | US | disclosed |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-03-26 | — | — | US | disclosed |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | NATIONAL SCIENCE FOUNDATION | 2017-06-08 | — | — | US | disclosed |
| US-9388131-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-19 | — | — | US | disclosed |
| US-9012658-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.