Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656359 | 1.00 | HTT (0.61) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL13209087 | 1.00 | HTT (0.61) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL30674371 | 1.00 | HTT (0.61) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL30674383 | 0.91 | MAOA (0.58) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL14463143 | 0.85 | HTT (0.57) | HTTALDH1A1XBP1RAB9ATAS2R14 | |
| SCHEMBL16656767 | 0.85 | HTT (0.57) | HTTALDH1A1XBP1RAB9ATAS2R14 | |
| SCHEMBL16656814 | 0.85 | HTT (0.57) | HTTALDH1A1XBP1RAB9ATAS2R14 | |
| SCHEMBL13209090 | 0.85 | ALDH1A1 (0.57) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL13209092 | 0.81 | ALDH1A1 (0.58) | HTTALDH1A1XBP1RAB9AMAOA | |
| SCHEMBL12124859 | 0.80 | HTT (0.57) | HTTALDH1A1XBP1RAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | NATIONAL SCIENCE FOUNDATION | 2017-06-08 | — | — | US | disclosed |
| US-9012658-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | HTT 4055/4885ALDH1A1 1530/4885XBP1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.