SCHEMBL16656874

CO[C@@H](O[C@H]1C(COS(=O)(=O)O)O[C@@H](O[C@H]2C(C(=O)O)O[C@@H](O[C@H]3C(COS(=O)(=O)O)O[C@@H](O)[C@@H](C)C3O)[C@@H](OS(=O)(=O)O)C2O)[C@@H](C)C1O)OS(=O)(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	6/20	0.52

▸	SERPINC1	P01008	2/20	0.46

▸	CXCL10	P02778	1/20	0.42

▸	CXCL8	P10145	1/20	0.42

▸	CCL2	P13500	1/20	0.42

▸	CCL5	P13501	1/20	0.42

▸	CXCL12	P48061	1/20	0.42

▸	BDNF	P23560	3/20	0.39

▸	PTN	P21246	2/20	0.39

▸	MDK	P21741	2/20	0.39

▸	FGF1	P05230	3/20	0.36

▸	FGF2	P09038	1/20	0.36

▸	HPSE	Q9Y251	5/20	0.36

▸	F2	P00734	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16656905	0.83	F10 (0.63)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL12360709	0.83	F10 (0.62)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL15417563	0.83	F10 (0.53)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16656904	0.80	F10 (0.60)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16656848	0.80	F10 (0.60)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL14817756	0.79	F10 (0.69)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL12360708	0.78	F10 (0.46)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16656900	0.76	F10 (0.32)	F10
SCHEMBL17167857	0.76	F10 (0.53)	F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL17167551	0.76	F10 (0.55)	F10SERPINC1CXCL10CXCL8CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9012413-B2	FGF receptor-activating N-acyl octasaccharides, preparation thereof, and therapeutic use thereof	SANOFI (FR)	2015-04-21	—	—	US	disclosed