SCHEMBL16657553

SCHEMBL16657553

C=C(O)C(CCCCNC(C)C)NC(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 18/20 0.61
▸ NAALAD2 Q9Y3Q0 2/20 0.55
▸ RIMKLA Q8IXN7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19351793 0.93 FOLH1 (0.69) FOLH1NAALAD2RIMKLA
SCHEMBL16657558 0.93 FOLH1 (0.69) FOLH1NAALAD2RIMKLA
SCHEMBL19351949 0.93 FOLH1 (0.69) FOLH1NAALAD2RIMKLA
SCHEMBL19351945 0.93 FOLH1 (0.69) FOLH1NAALAD2RIMKLA
SCHEMBL19351795 0.93 FOLH1 (0.69) FOLH1NAALAD2RIMKLA
SCHEMBL23567812 0.88 FOLH1 (0.63) FOLH1NAALAD2RIMKLA
SCHEMBL10134716 0.83 FOLH1 (0.60) FOLH1NAALAD2RIMKLA
SCHEMBL15383531 0.83 FOLH1 (0.60) FOLH1NAALAD2RIMKLA
SCHEMBL19788649 0.82 FOLH1 (0.54) FOLH1NAALAD2RIMKLA
SCHEMBL15158795 0.81 FOLH1 (0.60) FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11638765-B2 Double-labeled probe for molecular imaging and use thereof DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2023-05-02 — — US disclosed
US-20150110715-A1 Double-Labeled Probe for Molecular Imaging and Use Thereof RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) 2015-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150110715-A1 Double-Labeled Probe for Molecular Imaging and Use Thereof CD47, ANXA5, CD44 FOLH1 36/4885NAALAD2 2184/4885RIMKLA 3722/4885
US-11638765-B2 Double-labeled probe for molecular imaging and use thereof ANXA1, ANXA5, CD47 FOLH1 200/4885NAALAD2 3824/4885RIMKLA 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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