Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 18/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19351793 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16657558 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19351945 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19351949 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19351795 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL26179013 | 0.84 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL23567812 | 0.83 | FOLH1 (0.63) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16657553 | 0.82 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL20018480 | 0.82 | FOLH1 (0.78) | FOLH1 | |
| SCHEMBL24004559 | 0.81 | SMN1; SMN2 (0.52) | FOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |