SCHEMBL1665813

SCHEMBL1665813

NC(=O)C(c1cccc2ccccc12)C(C(N)=O)c1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP1A2 P05177 1/20 0.55
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALOX5 P09917 1/20 0.46
ACP3 P15309 4/20 0.46
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
AOC3 Q16853 1/20 0.42
MTNR1A P48039 1/20 0.41
CTNNB1 P35222 1/20 0.41
LMNA P02545 1/20 0.41
AURKA O14965 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243896 0.93 ALDH1A1 (0.53) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL25368292 0.84 ALDH1A1 (0.44) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL7302864 0.82 ALDH1A1 (0.43) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL28140482 0.82 ALDH1A1 (0.52) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL6894430 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL6897764 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL1285411 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL2369774 0.81 ALDH1A1 (0.57) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL9560093 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19CYP1A2GAA
SCHEMBL15389969 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19CYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733672-B1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2023-03-22 EP disclosed
EP-3733672-A1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-11-04 EP disclosed
WO-2011043404-A1 HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-14 WO disclosed