SCHEMBL1665864

SCHEMBL1665864

CC(=O)c1ccc(C(C)=O)c(C(C)=O)c1C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
HPGD P15428 5/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 4/20 0.39
TSHR P16473 1/20 0.38
HSD17B1 P14061 1/20 0.38
PBRM1 Q86U86 1/20 0.37
NSD2 O96028 1/20 0.37
POLB P06746 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883365 0.87 THRB (0.56) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL1667194 0.87 THRB (0.39) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL28540780 0.87 THRB (0.39) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL4075879 0.85 CYP1A2 (0.44) THRBALDH1A1ALOX15KDM4ETSHR
SCHEMBL7798942 0.84 THRB (0.46) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL15658811 0.83 HPGD (0.37) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL600052 0.82 THRB (0.56) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL28845451 0.82 THRB (0.39) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL8743373 0.82 THRB (0.35) THRBHPGDCYP3A4MEN1KMT2A
SCHEMBL8581087 0.80 THRB (0.38) THRBHPGDCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114308026-A Graphite alkynyl diatomic catalyst and preparation method and application thereof 天津理工大学 2022-04-12 CN claimed
CN-114308026-A Graphite alkynyl diatomic catalyst and preparation method and application thereof 天津理工大学 2022-04-12 CN disclosed
CN-111500227-A UV curable epoxy/acrylate adhesive compositions 3M创新有限公司 2020-08-07 CN disclosed
CN-107709497-B UV curable epoxy/acrylate adhesive compositions 3M创新有限公司 2020-07-17 CN disclosed
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R THRB 2944/4885HPGD 3116/4885CYP3A4 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.