SCHEMBL16658794

SCHEMBL16658794

CCCCCCC/C=C/C=C/C(=O)NCCC

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.70
CNR2 P34972 5/20 0.70
FAAH O00519 4/20 0.54
FASN P49327 1/20 0.53
KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1915904 0.98 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL1916424 0.98 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL11222635 0.98 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL3372474 0.93 CNR1 (0.70) CNR1CNR2FAAHFASNKDM4E
SCHEMBL17556035 0.92 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL4886505 0.92 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL4886501 0.92 CNR1 (0.68) CNR1CNR2FAAHFASNKDM4E
SCHEMBL7638596 0.90 CNR1 (0.67) CNR1CNR2FAAH
SCHEMBL17091577 0.90 CNR1 (0.67) CNR1CNR2FAAH
SCHEMBL5884581 0.89 CNR1 (0.65) CNR1CNR2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9199948-B2 1,3-benzoxazol-2(3H)-ones and their use as medicaments and cosmetics DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-12-01 US disclosed
US-9199948-B2 1,3-benzoxazol-2(3H)-ones and their use as medicaments and cosmetics DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-12-01 US disclosed
US-20150111935-A1 NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-04-23 US disclosed
US-20150111935-A1 NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111935-A1 NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS TRPV1, TRPA1, P2RX3 CNR1 195/4885CNR2 99/4885FAAH 193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.