Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16182668 | 0.90 | MAPT (0.57) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL3976179 | 0.89 | MAPT (0.56) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11775317 | 0.86 | MAPT (0.57) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8769958 | 0.83 | KDM4E (0.52) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6567089 | 0.83 | KDM4E (0.52) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1665977 | 0.83 | MAPT (0.70) | MAPTALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL28482368 | 0.82 | MAPT (0.54) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL31272384 | 0.82 | ALDH1A1 (0.68) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2291597 | 0.82 | MAPT (0.60) | MAPTALDH1A1KDM4ETDP1METAP2 | |
| SCHEMBL20484459 | 0.82 | MAPT (0.60) | MAPTALDH1A1KDM4EMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314581-B1 | A process for preparing benzo[b]thiophene derivatives | HEXAL AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011047877-A1 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314581-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-04-27 | — | — | EP | disclosed |
| EP-0311735-A2 | Heterocycle sulfone oligomers and blends | The Boeing Company (US) | 1989-04-19 | — | — | EP | disclosed |