Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356577 | 0.85 | FAAH (0.44) | FAAHHRH4MAPK14 | |
| SCHEMBL15343420 | 0.83 | FAAH (0.43) | FAAHHRH4 | |
| SCHEMBL16660258 | 0.79 | FAAH (0.51) | FAAHHRH4 | |
| SCHEMBL15473118 | 0.79 | FAAH (0.43) | FAAHHRH4 | |
| SCHEMBL15356594 | 0.78 | ESR1 (0.56) | FAAHHRH4 | |
| SCHEMBL15343084 | 0.78 | FAAH (0.46) | FAAHHRH4 | |
| SCHEMBL3405987 | 0.78 | FAAH (0.76) | FAAH | |
| SCHEMBL4294870 | 0.78 | FAAH (0.76) | FAAH | |
| SCHEMBL15343058 | 0.78 | PRKDC (0.47) | FAAHHRH4 | |
| SCHEMBL15473058 | 0.77 | FAAH (0.49) | FAAHHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150111871-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111871-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | FAAH 3955/4885HRH4 2433/4885MAPK14 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.