Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939289 | 0.76 | — | — | |
| SCHEMBL7743902 | 0.74 | CRBN (0.42) | CRBNTAS2R38 | |
| SCHEMBL27253360 | 0.73 | — | — | |
| SCHEMBL8740654 | 0.72 | MAPT (0.46) | — | |
| SCHEMBL18950872 | 0.72 | CRBN (0.31) | CRBN | |
| SCHEMBL19646891 | 0.72 | — | — | |
| SCHEMBL10596832 | 0.72 | CRBN (0.38) | CRBNNFKB1TAS2R38 | |
| Alcohol SCHEMBL8740653 | 0.71 | — | — | |
| SCHEMBL21008263 | 0.70 | PTGS1 (0.33) | CRBNNFKB1TAS2R38 | |
| SCHEMBL978856 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928456-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MIIKANA THERAPEUTICS INC (US) | 2015-04-22 | — | — | EP | disclosed |