Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766798 | 0.83 | MEN1 (0.32) | — | |
| SCHEMBL18629944 | 0.79 | — | — | |
| SCHEMBL19062666 | 0.76 | — | — | |
| SCHEMBL18483031 | 0.73 | TAS2R38 (0.32) | — | |
| SCHEMBL15382252 | 0.72 | TAS2R38 (0.34) | CRBN | |
| SCHEMBL13972727 | 0.72 | — | — | |
| SCHEMBL16660272 | 0.72 | CRBN (0.32) | CRBN | |
| SCHEMBL13497222 | 0.72 | — | — | |
| SCHEMBL10536655 | 0.72 | — | — | |
| SCHEMBL18286973 | 0.71 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981536-B1 | N-PHENYL-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UC (IE) | 2017-06-14 | — | — | EP | disclosed |