SCHEMBL16660310

SCHEMBL16660310

O=C(Oc1ccc(-c2ccc(C(=O)Oc3cc(-c4c(OC(=O)c5ccc(-c6ccc(OC(=O)c7ccc(O)cc7)cc6)cc5)ccc5ccccc45)c4ccccc4c3)cc2)cc1)c1ccc(O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
SENP1 Q9P0U3 1/20 0.38
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
GPR84 Q9NQS5 2/20 0.37
ESR1 P03372 5/20 0.36
ESR2 Q92731 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
PARP10 Q53GL7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660314 0.97 KMT2A (0.46) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749083 0.94 KMT2A (0.45) KMT2AMEN1MAPTTDP1SENP1
SCHEMBL16749085 0.94 KMT2A (0.46) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749084 0.93 KMT2A (0.47) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749087 0.92 KMT2A (0.43) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL17432988 0.90 MAPT (0.46) KMT2AMEN1MAPTTDP1PDGFRB
SCHEMBL16749181 0.88 KMT2A (0.43) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL17433030 0.86 KMT2A (0.49) KMT2AMEN1MAPTTDP1SENP1
SCHEMBL17432991 0.86 SENP1 (0.49) KMT2AMEN1MAPTTDP1SENP1
SCHEMBL17432932 0.86 KMT2A (0.49) KMT2AMEN1MAPTTDP1SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed