SCHEMBL16660314

SCHEMBL16660314

O=C(Oc1ccc(C(=O)Oc2ccc(C(=O)Oc3cc(-c4c(OC(=O)c5ccc(OC(=O)c6ccc(OC(=O)c7ccc(O)cc7)cc6)cc5)ccc5ccccc45)c4ccccc4c3)cc2)cc1)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.46
MEN1 O00255 6/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
ESR1 P03372 6/20 0.38
CASP3 P42574 2/20 0.37
SENP8 Q96LD8 2/20 0.37
SENP7 Q9BQF6 2/20 0.37
SENP6 Q9GZR1 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PARP10 Q53GL7 1/20 0.37
ESR2 Q92731 4/20 0.37
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36
NPC1 O15118 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749083 0.98 KMT2A (0.45) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16749085 0.97 KMT2A (0.46) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16660310 0.97 KMT2A (0.43) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749084 0.96 KMT2A (0.47) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749087 0.95 KMT2A (0.43) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL16749181 0.91 KMT2A (0.43) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL17433030 0.89 KMT2A (0.49) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL17432932 0.89 KMT2A (0.49) KMT2AMEN1MAPTTDP1FNTA
SCHEMBL17270108 0.89 ESR1 (0.47) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16660340 0.88 KMT2A (0.54) KMT2AMEN1MAPTTDP1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed