SCHEMBL16660340

SCHEMBL16660340

O=C(Oc1ccc(C(=O)Oc2ccc3cc(C(=O)Oc4ccc5ccccc5c4-c4c(OC(=O)c5ccc6cc(OC(=O)c7ccc(OC(=O)c8ccc(O)cc8)cc7)ccc6c5)ccc5ccccc45)ccc3c2)cc1)c1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.54
MEN1 O00255 6/20 0.54
MAPT P10636 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
ESR1 P03372 5/20 0.46
CASP3 P42574 2/20 0.45
SENP8 Q96LD8 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
SENP6 Q9GZR1 2/20 0.45
HGFAC Q04756 2/20 0.43
F12 P00748 2/20 0.43
TMPRSS2 O15393 1/20 0.43
MLNR O43193 1/20 0.43
ALDH1A1 P00352 1/20 0.43
F2 P00734 1/20 0.43
C1R P00736 1/20 0.43
F10 P00742 1/20 0.43
PLG P00747 1/20 0.43
LMNA P02545 1/20 0.43
ITGB3 P05106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660305 0.99 KMT2A (0.55) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16660301 0.94 KMT2A (0.48) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL17433030 0.94 KMT2A (0.49) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL17432932 0.94 KMT2A (0.49) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16749085 0.92 KMT2A (0.46) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16749084 0.91 KMT2A (0.47) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL17432988 0.90 MAPT (0.46) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL4943531 0.89 MAPT (0.46) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16660338 0.88 KMT2A (0.49) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL16660314 0.88 KMT2A (0.46) KMT2AMEN1MAPTTDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed