SCHEMBL4943531

SCHEMBL4943531

O=C(Oc1ccc2ccccc2c1-c1c(OC(=O)c2ccc(O)cc2)ccc2ccccc12)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
ESR1 P03372 5/20 0.45
ESR2 Q92731 5/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
GAA P10253 2/20 0.45
JAK2 O60674 1/20 0.45
USP2 O75604 1/20 0.45
ALOX15 P16050 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SENP1 Q9P0U3 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
POLB P06746 1/20 0.44
DHFR P00374 1/20 0.43
TYMS P04818 1/20 0.43
PTGES O14684 1/20 0.42
ALOX5 P09917 1/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17432991 0.96 SENP1 (0.49) MAPTESR1ESR2KMT2AMEN1
SCHEMBL17432932 0.96 KMT2A (0.49) MAPTESR1ESR2KMT2AMEN1
SCHEMBL17433030 0.96 KMT2A (0.49) MAPTESR1ESR2KMT2AMEN1
SCHEMBL17432988 0.92 MAPT (0.46) MAPTESR1ESR2KMT2AMEN1
SCHEMBL16660305 0.91 KMT2A (0.55) MAPTESR1ESR2KMT2AMEN1
SCHEMBL16660338 0.90 KMT2A (0.49) MAPTESR1ESR2KMT2AMEN1
SCHEMBL16660340 0.89 KMT2A (0.54) MAPTESR1ESR2KMT2AMEN1
SCHEMBL14996396 0.89 ESR1 (0.50) MAPTESR1ESR2KMT2AMEN1
SCHEMBL16660304 0.89 MMP3 (0.43) MAPTESR1ESR2KMT2AMEN1
SCHEMBL16236952 0.89 MAPT (0.57) MAPTESR1ESR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed
US-7413782-B2 Polymerizing binaphthalene derivatives CHISSO CORPORATION (JP) 2008-08-19 US disclosed
US-20050179005-A1 Polymerizing binaphthalene derivatives JNC PETROCHEMICAL CORPORATION (JP) 2005-08-18 US disclosed