Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986163 | 0.96 | KMT2A (0.36) | GBA1KMT2AMAPTPRSS1ACR | |
| SCHEMBL5961823 | 0.94 | KMT2A (0.35) | GBA1KMT2AMAPTPRSS1ACR | |
| SCHEMBL15480714 | 0.91 | THRB (0.45) | KMT2AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13289441 | 0.91 | KMT2A (0.37) | GBA1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL19759250 | 0.89 | MAPT (0.35) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13226628 | 0.88 | HIF1A (0.34) | KMT2AMAPTALDH1A1POLBLMNA | |
| SCHEMBL11986078 | 0.88 | MAPT (0.35) | KMT2AMAPTALDH1A1POLBLMNA | |
| SCHEMBL14088490 | 0.87 | KMT2A (0.36) | GBA1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14588420 | 0.86 | THRB (0.43) | KMT2AMAPTALDH1A1POLBLMNA | |
| SCHEMBL18200237 | 0.86 | THRB (0.43) | KMT2AMAPTALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505980-B2 | Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment | JNC CORPORATION (JP) | 2016-11-29 | — | — | US | disclosed |
| US-20150108401-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT | JNC CORPORATION (JP) | 2015-04-23 | — | — | US | disclosed |