Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | ACR | P10323 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986163 | 0.98 | KMT2A (0.36) | KMT2AMAPTTHRBMEN1CCNC | |
| SCHEMBL16660342 | 0.94 | GBA1 (0.40) | KMT2AMAPTGBA1PDGFRBPDGFRA | |
| SCHEMBL15480714 | 0.93 | THRB (0.45) | KMT2AMAPTTHRBMEN1TDP1 | |
| SCHEMBL13289441 | 0.93 | KMT2A (0.37) | KMT2AMAPTTHRBMEN1TDP1 | |
| SCHEMBL19759250 | 0.91 | MAPT (0.35) | KMT2AMAPTTHRBMEN1TDP1 | |
| SCHEMBL13226628 | 0.90 | HIF1A (0.34) | KMT2AMAPTTHRBMEN1TDP1 | |
| SCHEMBL11986078 | 0.90 | MAPT (0.35) | KMT2AMAPTTHRBMEN1TDP1 | |
| SCHEMBL5961822 | 0.89 | KMT2A (0.34) | KMT2AMAPTTHRBMEN1CCNC | |
| SCHEMBL18200237 | 0.88 | THRB (0.43) | KMT2AMAPTTHRBTDP1L3MBTL1 | |
| SCHEMBL14588420 | 0.88 | THRB (0.43) | KMT2AMAPTTHRBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | CHISSO CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7919648-B2 | Lateral α-substituted acrylate compound and polymer thereof | CHISSO CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7597945-B2 | Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties | CHISSO CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7488519-B2 | Polymerizable liquid crystal composition | CHISSO CORPORATION (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20080241431-A1 | Polymerizable liquid crystal composition | CHISSO CORPORATION | 2008-10-02 | — | — | US | disclosed |
| US-7413782-B2 | Polymerizing binaphthalene derivatives | CHISSO CORPORATION (JP) | 2008-08-19 | — | — | US | disclosed |
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
| US-7157124-B2 | Polymerizable compounds and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | LEF1, AFF1, CNKSR1 | KMT2A 1856/4885MAPT 3921/4885THRB 1814/4885 |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | AFF1, CNKSR1, LEF1 | KMT2A 922/4885MAPT 3961/4885THRB 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.