SCHEMBL16660501

SCHEMBL16660501

C=C(C)C(=O)Oc1ccc(OC(C)OC2Cc3ccccc3C2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
KMT2A Q03164 3/20 0.41
ATM Q13315 1/20 0.41
FFAR1 O14842 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
LMNA P02545 3/20 0.33
GAA P10253 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPY5R Q15761 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
LIPE Q05469 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 3/20 0.32
HPGD P15428 2/20 0.32
MTNR1A P48039 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999005 0.84 ELANE (0.34) ELANEKMT2AATM
SCHEMBL92238 0.81 IDO1 (0.36) ELANEFFAR1MTNR1AMTNR1BGRM7
SCHEMBL16660472 0.78 MTNR1A (0.38) ELANEKMT2AATMMTNR1AMTNR1B
SCHEMBL16660465 0.78 ELANE (0.47) ELANEKMT2AATMNPC1RAB9A
SCHEMBL12021615 0.77 ELANE (0.38) ELANEKMT2AFFAR1NPC1RAB9A
SCHEMBL10870371 0.75 ELANE (0.51) ELANEKMT2AATMNPC1RAB9A
SCHEMBL16660502 0.75 ELANE (0.47) ELANEKMT2AATMFFAR1NPC1
SCHEMBL23332996 0.74 POLB (0.39) ELANEKMT2AATMNPC1RAB9A
SCHEMBL9999362 0.74 ELANE (0.43) ELANEKMT2AATMLMNAGAA
SCHEMBL72212 0.74 IDO1 (0.38) ELANEFFAR1MTNR1AMTNR1BGRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017918-B2 Monomer, polymer, chemically amplified positive resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-04-28 US disclosed