SCHEMBL16660465

SCHEMBL16660465

C=C(C)C(=O)Oc1ccc(OC(C)OC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.47
KMT2A Q03164 4/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 1/20 0.36
GAA P10253 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PPARG P37231 4/20 0.32
PPARA Q07869 4/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999362 0.95 ELANE (0.43) ELANEKMT2AATMPOLBGAA
SCHEMBL16660501 0.78 ELANE (0.47) ELANEKMT2AATMGAAALDH1A1
SCHEMBL12021560 0.77 ELANE (0.38) ELANEKMT2APOLBGAAALDH1A1
SCHEMBL10870371 0.75 ELANE (0.51) ELANEKMT2AATMPOLBGAA
SCHEMBL16660467 0.75 ELANE (0.47) ELANEKMT2AATMPOLBGAA
SCHEMBL11964375 0.75 ALDH1A1 (0.34) KMT2AALDH1A1LMNATSHR
SCHEMBL16660472 0.73 MTNR1A (0.38) ELANEKMT2AATM
SCHEMBL31567542 0.73 POLB (0.55) ELANEKMT2APOLBGAAALDH1A1
SCHEMBL2775729 0.73 POLB (0.55) ELANEKMT2APOLBGAAALDH1A1
SCHEMBL9963789 0.72 ELANE (0.48) ELANEKMT2AATMPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017918-B2 Monomer, polymer, chemically amplified positive resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-04-28 US disclosed