Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660711 | 0.96 | TRPV4 (0.46) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660722 | 0.88 | IKBKE (0.39) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660715 | 0.87 | TRPV4 (0.42) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660712 | 0.84 | LRRK2 (0.38) | NAMPTNPC1RAB9ASMN1; SMN2NR3C1 | |
| SCHEMBL16660720 | 0.84 | IKBKE (0.37) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660713 | 0.84 | NAMPT (0.39) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660721 | 0.84 | NAMPT (0.39) | NAMPTNPC1RAB9ASMN1; SMN2NR3C1 | |
| SCHEMBL16660710 | 0.82 | IKBKE (0.39) | NAMPTNPC1RAB9ASMN1; SMN2LRRK2 | |
| SCHEMBL15472433 | 0.76 | NAMPT (0.44) | NAMPTNPC1RAB9ASMN1; SMN2NR3C1 | |
| SCHEMBL15472431 | 0.76 | NAMPT (0.44) | TRPV4NAMPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015055497-A1 | SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2015-04-23 | — | — | WO | disclosed |