Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660722 | 0.88 | IKBKE (0.39) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660714 | 0.84 | TRPV4 (0.45) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660711 | 0.83 | TRPV4 (0.46) | LRRK2NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16660715 | 0.81 | TRPV4 (0.42) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660720 | 0.78 | IKBKE (0.37) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660710 | 0.76 | IKBKE (0.39) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660713 | 0.76 | NAMPT (0.39) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL16660721 | 0.74 | NAMPT (0.39) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL13731080 | 0.72 | NAMPT (0.41) | LRRK2NAMPTNPC1RAB9AIKBKE | |
| SCHEMBL433546 | 0.72 | RAB9A (0.46) | LRRK2NAMPTNPC1RAB9AIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015055497-A1 | SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2015-04-23 | — | — | WO | disclosed |