Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790076 | 0.81 | AAK1 (0.46) | AAK1DGAT1 | |
| SCHEMBL20428567 | 0.80 | TMPRSS15 (0.43) | TMPRSS15DGAT1 | |
| SCHEMBL16660998 | 0.76 | HCRTR1 (0.36) | TMPRSS15DGAT1DYRK1A | |
| SCHEMBL16787610 | 0.72 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL20428832 | 0.69 | TMPRSS15 (0.42) | TMPRSS15DGAT1 | |
| SCHEMBL15293797 | 0.69 | DGAT1 (0.49) | AAK1DGAT1 | |
| SCHEMBL15293916 | 0.69 | DGAT1 (0.46) | AAK1DGAT1 | |
| SCHEMBL10177236 | 0.69 | DGAT1 (0.48) | AAK1DGAT1 | |
| SCHEMBL20428637 | 0.68 | HCRTR1 (0.38) | DGAT1DYRK1A | |
| SCHEMBL10177482 | 0.67 | DGAT1 (0.48) | AAK1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |