Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484883 | 1.00 | TSHR (0.59) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL26262555 | 0.85 | CA1 (0.52) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL1429283 | 0.84 | TSHR (0.58) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL305694 | 0.84 | TSHR (0.62) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL1028048 | 0.82 | CA1 (0.57) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL21831286 | 0.82 | CA1 (0.57) | TSHRCA1CA2TDP1CA12 | |
| Benzene SCHEMBL28351738 | 0.82 | TSHR (0.85) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL15441153 | 0.81 | TSHR (0.57) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL198552 | 0.81 | CA1 (0.55) | TSHRCA1CA2TDP1CA12 | |
| SCHEMBL7518106 | 0.81 | TSHR (0.48) | TSHRCA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | disclosed |