SCHEMBL1666513

SCHEMBL1666513

NC(CCc1ccc(Oc2ccc(O)cc2)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.56
PCNA P12004 1/20 0.53
LTA4H P09960 2/20 0.48
GRIK1 P39086 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
GRIA4 P48058 1/20 0.47
GRIK2 Q13002 1/20 0.47
GRIK3 Q13003 1/20 0.47
MMP12 P39900 1/20 0.46
MMP13 P45452 1/20 0.46
KIF11 P52732 1/20 0.46
FFAR1 O14842 1/20 0.45
PARP10 Q53GL7 1/20 0.45
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
EGFR P00533 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9394667 0.90 SLC7A5 (0.67) SLC7A5GRIK1GRIA1GRIA2GRIA3
SCHEMBL1666620 0.90 SLC7A5 (0.67) SLC7A5GRIK1GRIA1GRIA2GRIA3
SCHEMBL1768639 0.90 SLC7A5 (0.67) SLC7A5GRIK1GRIA1GRIA2GRIA3
Bromide SCHEMBL29399073 0.89 SLC7A5 (0.65) SLC7A5GRIK1GRIA1GRIA2GRIA3
Bromide SCHEMBL919214 0.89 SLC7A5 (0.65) SLC7A5GRIK1GRIA1GRIA2GRIA3
SCHEMBL22851020 0.87 SLC7A5 (0.51) SLC7A5PCNALTA4HGRIK1GRIA1
SCHEMBL285216 0.84 SLC7A5 (0.80) SLC7A5PCNAKDM4EUSP2EGFR
SCHEMBL30622075 0.84 SLC7A5 (0.80) SLC7A5PCNAKDM4EUSP2EGFR
SCHEMBL285217 0.84 SLC7A5 (0.80) SLC7A5PCNAKDM4EUSP2EGFR
SCHEMBL29556905 0.84 SLC7A5 (0.80) SLC7A5PCNAKDM4EUSP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118011-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-14 US disclosed
EP-3461855-B1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES UNIV RUTGERS (US) 2020-05-27 EP disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 US disclosed
EP-3461855-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2019-04-03 EP disclosed
US-10202490-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-12 US disclosed
EP-2486081-B1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES UNIV RUTGERS (US) 2018-12-05 EP disclosed
US-20170158819-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2017-06-08 US disclosed
US-9605112-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-28 US disclosed
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-09-06 US disclosed
EP-2486081-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES Rutgers, The State University of New Jersey (US) 2012-08-15 EP disclosed
WO-2011044567-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES MATR3, MIF, BMP2 SLC7A5 2373/4885PCNA 187/4885LTA4H 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.