Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.80 |
| ▸ | PCNA | P12004 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285217 | 1.00 | SLC7A5 (0.80) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| SCHEMBL29556905 | 1.00 | SLC7A5 (0.80) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| SCHEMBL30622075 | 1.00 | SLC7A5 (0.80) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| Iodide SCHEMBL4670395 | 0.98 | SLC7A5 (0.77) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| SCHEMBL29455798 | 0.98 | SLC7A5 (0.77) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| SCHEMBL28173375 | 0.98 | SLC7A5 (0.77) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| Iodide SCHEMBL4672201 | 0.98 | SLC7A5 (0.77) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| 2-Mercaptoethanol SCHEMBL27826214 | 0.91 | SLC7A5 (0.67) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| Tyrosine SCHEMBL1580 | 0.89 | SLC7A5 (1.00) | SLC7A5PCNAPTGS1KDM4EUSP2 | |
| Tyrosine SCHEMBL11676367 | 0.89 | SLC7A5 (1.00) | SLC7A5PCNAPTGS1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109387642-A | A kind of detection reagent detecting trilute | 河北艾驰生物科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-108463548-A | Method for producing T cell from stem cell and immunotherapy method using the T cell | 加利福尼亚大学董事会 | 2018-08-28 | — | — | CN | claimed |
| CN-108431209-A | Derived and mature hepatocyte types of liver stem cells and uses thereof | 新加坡科技研究局 | 2018-08-21 | — | — | CN | claimed |
| CN-104531607-B | The primary bronchiole epithelial cell of dog and its application in immortalized cells is prepared | 南京农业大学 | 2017-11-07 | — | — | CN | claimed |
| CN-107075469-A | Mammal limbal stem cell, its production method and its purposes of culture | 加利福尼亚大学董事会 | 2017-08-18 | — | — | CN | claimed |
| CN-106456672-A | Functional oligodendrocytes derived from pluripotent stem cells and methods of making and using the same | 纽约干细胞基金会有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-20100075435-A1 | BIOTINYLATED THYROXINE | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | claimed |
| CN-1218755-C | Stem cell regenerating surface cornea and its application in corneal transplantation | KEYU UNION STEM CELL BIOTECHNO (CN) | 2005-09-14 | — | — | CN | claimed |
| US-20040234592-A1 | Mixture containing thyroid hormone , ethanolamine and emulsifier | KARO BIO AB (SE) | 2004-11-25 | — | — | US | claimed |
| EP-1404413-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2004-04-07 | — | — | EP | claimed |
| WO-2002089917-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2002-11-14 | — | — | WO | claimed |
| US-20020123521-A1 | Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds | KOO, CATHERINE, DR | 2002-09-05 | — | — | US | claimed |
| US-6380255-B1 | TOPICALLY APPLYING TO SKIN THYROID HORMONE COMPOUND TOGETHER WITH A BASE FOR THERAPY OF SKIN ATROPHY | KARO BIO AB (SE) | 2002-04-30 | — | — | US | claimed |
| WO-2002005834-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE AGONIST COMPOUNDS FOR TREATING DERMIS CONDITIONS | KARO BIO AB (SE) | 2002-01-24 | — | — | WO | claimed |
| US-6221911-B1 | REDUCING SUBCUTANEOUS FAT DEPOSITS IN A SUBJECT; IMPROVING THE SKIN CONDITION OF A SUBJECT | KARO BIO AB (SE) | 2001-04-24 | — | — | US | claimed |
| EP-0831769-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1998-04-01 | — | — | EP | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| WO-1996040048-A9 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | — | 1997-03-27 | — | — | WO | claimed |
| WO-1996040048-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1996-12-19 | — | — | WO | claimed |
| US-4299812-A | Immunoassay of thyroxine in neonates using dried blood samples | DIAGNOSTIC PRODUCTS CORP. (US) | 1981-11-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075435-A1 | BIOTINYLATED THYROXINE | TPO, TSHR, THRB | SLC7A5 67/4885PCNA 3006/4885PTGS1 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.