Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665096 | 0.95 | SLC2A1 (0.45) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL1666531 | 0.95 | SLC2A1 (0.45) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL1667499 | 0.88 | RAB9A (0.49) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL6125945 | 0.86 | PDE7A (0.40) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL1664628 | 0.86 | SLC2A1 (0.42) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL1664041 | 0.85 | PDE7A (0.41) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL6126025 | 0.84 | NPC1 (0.47) | MAPTALDH1A1MCL1LCKMAPK14 | |
| SCHEMBL6126449 | 0.84 | NPC1 (0.47) | MAPTALDH1A1MCL1LCKMAPK14 | |
| SCHEMBL1667500 | 0.84 | RAB9A (0.52) | MAPTALDH1A1MCL1KMT2AKDM4E | |
| SCHEMBL1664832 | 0.84 | PDE7A (0.41) | MAPTALDH1A1KMT2ALCKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |