Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20071134 | 0.85 | MC4R (0.53) | ALDH1A1KDM4EMAPTNCF1 | |
| SCHEMBL21158867 | 0.83 | NCF1 (0.42) | ALDH1A1KDM4EMAPTNCF1TSHR | |
| SCHEMBL20148587 | 0.80 | KDM4E (0.47) | ALDH1A1KDM4EKMT2ATDP1NCF1 | |
| SCHEMBL22811852 | 0.80 | NCF1 (0.40) | ALDH1A1KDM4EMAPTNCF1TSHR | |
| SCHEMBL22811853 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL21158864 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL20154569 | 0.79 | NCF1 (0.40) | ALDH1A1KDM4EMAPTNCF1TSHR | |
| SCHEMBL17010820 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL20311160 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10819395 | 0.73 | KMT2A (0.53) | ALDH1A1KDM4EMAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313096-A1 | NEW COMPOUNDS V | AstraZeneca AB (Publ) (SE) | 2011-04-27 | — | — | EP | claimed |
| WO-2009147211-A1 | NEW COMPOUNDS V | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |