Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463601 | 0.81 | RPS6KA5 (0.37) | RPS6KA5 | |
| SCHEMBL29225057 | 0.81 | RPS6KA5 (0.37) | RPS6KA5 | |
| SCHEMBL4166238 | 0.72 | MAPT (0.33) | KDM4E | |
| SCHEMBL16665657 | 0.69 | RPS6KA5 (0.40) | RPS6KA5KDM4EBTKTYRO3DYRK1B | |
| SCHEMBL29174702 | 0.69 | RPS6KA5 (0.43) | RPS6KA5KDM4EBTK | |
| SCHEMBL29174727 | 0.68 | RPS6KA5 (0.43) | RPS6KA5KDM4EBTKTYRO3DYRK1B | |
| SCHEMBL25551891 | 0.68 | RPS6KA5 (0.42) | RPS6KA5BTK | |
| SCHEMBL30725466 | 0.68 | RPS6KA5 (0.43) | RPS6KA5KDM4EBTKTYRO3DYRK1B | |
| SCHEMBL1806705 | 0.67 | L3MBTL1 (0.40) | RPS6KA5KDM4EBTK | |
| SCHEMBL31006820 | 0.67 | RPS6KA5 (0.42) | RPS6KA5KDM4EBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058163-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-04-23 | — | — | WO | disclosed |