Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699016 | 0.79 | NFKB1 (0.35) | RPS6KA5 | |
| SCHEMBL30444276 | 0.73 | KDM4E (0.55) | RPS6KA5BTKKDM4ECYP1A2CYP2C9 | |
| SCHEMBL25820968 | 0.73 | KDM4E (0.55) | RPS6KA5BTKKDM4ECYP1A2CYP2C9 | |
| SCHEMBL30919628 | 0.73 | KDM4E (0.42) | RPS6KA5BTKKDM4ECYP1A2 | |
| SCHEMBL28149204 | 0.73 | CNR2 (0.41) | RPS6KA5PPARAIDO1BRAF | |
| SCHEMBL31006820 | 0.73 | RPS6KA5 (0.42) | RPS6KA5BTKKDM4E | |
| SCHEMBL17490482 | 0.72 | KDM4E (0.45) | RPS6KA5BTKKDM4E | |
| SCHEMBL7539390 | 0.70 | AHR (0.48) | BTKIDO1 | |
| SCHEMBL30919687 | 0.70 | BTK (0.40) | RPS6KA5BTKKDM4E | |
| SCHEMBL30919655 | 0.70 | ALDH1A1 (0.49) | RPS6KA5BTKKDM4ECYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |