Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 6/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | HCK | P08631 | 3/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.49 |
| ▸ | PRKDC | P78527 | 3/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.49 |
| ▸ | BTK | Q06187 | 6/20 | 0.46 |
| ▸ | RET | P07949 | 4/20 | 0.46 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.46 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665815 | 0.92 | SRC (0.49) | SRCLCKTEKKDREGFR | |
| SCHEMBL16665682 | 0.87 | EGFR (0.51) | SRCLCKKDREGFRPIK3CD | |
| SCHEMBL16665711 | 0.82 | PIK3CD (0.62) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL16665783 | 0.78 | EGFR (0.46) | SRCLCKKDREGFRPIK3CD | |
| SCHEMBL16655730 | 0.77 | ATR (0.70) | SRCLCKTEKKDREGFR | |
| SCHEMBL16665841 | 0.76 | ATR (0.61) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL16665849 | 0.73 | PIK3CD (0.53) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL16665809 | 0.73 | RET (0.43) | SRCLCKKDREGFRPIK3CD | |
| SCHEMBL13020084 | 0.71 | SRC (0.67) | SRCLCKTEKKDREGFR | |
| SCHEMBL16665739 | 0.70 | PIK3CD (0.51) | SRCKDREGFRPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |