SCHEMBL16666148

SCHEMBL16666148

O=C(O)Oc1ccc2c(c1)CC(NCC(O)c1cccc(Cl)c1)CC2

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 18/20 0.80
ADRB1 P08588 6/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4640099 0.89 ADRB3 (1.00) ADRB3ADRB1
SCHEMBL3873179 0.89 ADRB3 (1.00) ADRB3ADRB1
SCHEMBL3873178 0.89 ADRB3 (1.00) ADRB3ADRB1
SCHEMBL18086461 0.88 ADRB3 (0.71) ADRB3ADRB1
Hydrochloric Acid SCHEMBL3878377 0.88 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4639809 0.88 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL3878376 0.88 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4665229 0.88 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4665231 0.88 ADRB3 (0.98) ADRB3ADRB1
SCHEMBL10532036 0.87 ADRB3 (0.76) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015058053-A1 FUSED BENZAZEPINES FOR TREATMENT OF STUTTERING PSYADON PHARMACEUTICALS, INC. (US) 2015-04-23 WO disclosed